Alcohol metabolism in the human body is regulated by two key enzymes: alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Genetic variations in these enzymes, particularly in the ADH1B and ALDH2 genes, significantly affect alcohol processing and health risks.
The ADH1B variant (rs1229984) increases enzyme activity, rapidly converting alcohol into acetaldehyde, a toxic intermediate. Meanwhile, the ALDH2 variant (rs671) reduces enzyme efficiency, slowing acetaldehyde breakdown. This leads to its accumulation, causing facial flushing, nausea, and a higher risk of esophageal cancer.
REGISTRATION STATUS
Research Use Only
VitaSIRO solo™ ADH/ALDH SNP Assay
VitaSIRO solo™ – Molecular Diagnostics at Your Fingertips.
The VitaSIRO solo™ ADH/ALDH Assay provides a solution by offering a simple and rapid method for detecting key genetic variations. Through a non-invasive buccal swab and an automated testing process, The assay accurately identifies individual genetic predispositions to alcohol metabolism within 20 minutes. This valuable information empowers individuals and healthcare providers to make informed decisions about alcohol consumption, enabling personalized risk assessment and management strategies.
By understanding their genetic makeup, individuals can make more conscious choices about their alcohol intake, potentially reducing their risk of developing alcohol-related health issues.
Accessible
- Room Temperature Storage
- Non-invasive Sampling
- No additional equipment needed
Performance
- Targeting both ADL and ALDH genes
- Intuitive result interpretation with Ct value & fluorescence curve
Time Saving
- < 1 minutes hands-on time
- 20 minutes turnaround time
Diagnostic Procedure in 3 Steps
Collect
Collect sample
Lyse
Lyse the sample
thoroughly for 15 times
Transfer
Transfer the sample
Start Run
Results reported in
20 minutes
Intuitive Result Interpretation
VitaSIRO solo™ ADH/ALDH SNP Assay
Catalog No.
PCRBD1116
Technology
Real-Time PCR + Fluorescence Spectrum Detection
Quantity
20 test/box
Turnaround Time
20 minutes
Targets
ADH1B A & G; ALDH2 G & A genes
Specimen
Buccal Swab
Hands-on Time
< 1 minute
Kit Storage
5~25°C
